Biostatistics
We run the design, sample size, survival and diagnostic test analysis for clinical and epidemiological research, and write the report for ethics boards and peer review.
What we do
Study design and sample size. For case-control, cohort and cross-sectional designs we fix the method and the required sample size before data collection begins.
Survival analysis. Kaplan-Meier curves, log-rank comparisons and Cox regression for time-to-event outcomes.
Diagnostic accuracy and agreement. Sensitivity, specificity, ROC curves and cut-off selection; inter-rater and inter-method agreement.
Multivariable modelling. Control of confounders, examination of effect modifiers, and an explicit strategy for missing data.
What sets us apart
We talk before the data is collected. Design is the one thing that cannot be repaired at the analysis stage.
Ethics boards and peer review. The statistical section is written so that it answers the questions an ethics board and a reviewer will ask.
Reporting guidelines. Depending on the study type, the statistical items of CONSORT, STROBE or STARD are observed from the outset.
Limitations are written down. An assumption that is not met is not hidden; it is reported as an alternative method or as a limitation.